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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK3 All Species: 48.48
Human Site: Y236 Identified Species: 66.67
UniProt: Q00526 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00526 NP_001249.1 305 35046 Y236 G V T Q L P D Y K G S F P K W
Chimpanzee Pan troglodytes XP_523720 325 36841 Y256 G V T Q L P D Y K G S F P K W
Rhesus Macaque Macaca mulatta XP_001102596 305 34903 Y236 G V T Q L P D Y K G N F P K W
Dog Lupus familis XP_540442 303 34173 Y234 G V T Q L P D Y K G S F P K W
Cat Felis silvestris
Mouse Mus musculus Q80YP0 303 33870 Y235 G V S Q M P D Y Q S S F P K W
Rat Rattus norvegicus Q63699 298 33869 Y236 G V T S M P D Y K P S F P K W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P13863 303 34670 Y237 D V E S L Q D Y K N T F P K W
Frog Xenopus laevis P23437 297 33852 Y236 G V T T M P D Y K S T F P K W
Zebra Danio Brachydanio rerio NP_998571 298 34001 Y236 G V T S M P D Y K P S F P K W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23572 297 34420 Y237 G V T S L P D Y K N T F P C W
Honey Bee Apis mellifera XP_393450 299 34033 Y235 G V S Q L R D Y T S M F P R W
Nematode Worm Caenorhab. elegans P34556 332 38277 Y255 G V E S L P D Y K A T F P K W
Sea Urchin Strong. purpuratus XP_790847 299 34142 Y236 G V T S L P D Y K T S F P R W
Poplar Tree Populus trichocarpa XP_002306004 294 33768 N224 F R I L G T P N E D T W P G V
Maize Zea mays P23111 294 33816 N224 F R I L G T P N E Q S W P G V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 Y224 F R I M G T P Y E D T W R G V
Baker's Yeast Sacchar. cerevisiae P00546 298 34043 N232 F R V L G T P N E A I W P D I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 96.7 88.5 N.A. 82.6 74.7 N.A. N.A. 63.6 73.7 73.7 N.A. 62.9 67.2 58.1 69.5
Protein Similarity: 100 93.5 98.3 92.7 N.A. 91.8 84.5 N.A. N.A. 78 84.5 83.2 N.A. 76.7 80.6 69.5 82.6
P-Site Identity: 100 100 93.3 100 N.A. 73.3 80 N.A. N.A. 60 73.3 80 N.A. 73.3 60 73.3 80
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. 66.6 86.6 86.6 N.A. 80 73.3 80 86.6
Percent
Protein Identity: 65.2 64.2 N.A. 65.5 62.3 N.A.
Protein Similarity: 81.6 80.9 N.A. 81.3 77.7 N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 26.6 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % C
% Asp: 6 0 0 0 0 0 77 0 0 12 0 0 0 6 0 % D
% Glu: 0 0 12 0 0 0 0 0 24 0 0 0 0 0 0 % E
% Phe: 24 0 0 0 0 0 0 0 0 0 0 77 0 0 0 % F
% Gly: 71 0 0 0 24 0 0 0 0 24 0 0 0 18 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 18 0 0 0 0 0 0 0 6 0 0 0 6 % I
% Lys: 0 0 0 0 0 0 0 0 65 0 0 0 0 59 0 % K
% Leu: 0 0 0 18 53 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 6 24 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 18 0 12 6 0 0 0 0 % N
% Pro: 0 0 0 0 0 65 24 0 0 12 0 0 95 0 0 % P
% Gln: 0 0 0 36 0 6 0 0 6 6 0 0 0 0 0 % Q
% Arg: 0 24 0 0 0 6 0 0 0 0 0 0 6 12 0 % R
% Ser: 0 0 12 36 0 0 0 0 0 18 48 0 0 0 0 % S
% Thr: 0 0 53 6 0 24 0 0 6 6 36 0 0 0 0 % T
% Val: 0 77 6 0 0 0 0 0 0 0 0 0 0 0 18 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 24 0 0 77 % W
% Tyr: 0 0 0 0 0 0 0 83 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _